Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689470 | 0.78 | GRIN2B (0.50) | SMN1; SMN2 | |
| SCHEMBL5517169 | 0.77 | HRH1 (0.47) | CYP17A1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4588101 | 0.75 | TAAR1 (0.52) | CYP2C19KDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL18690746 | 0.72 | MALT1 (0.47) | CYP17A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18690747 | 0.72 | MALT1 (0.47) | CYP17A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1178369 | 0.71 | CA2 (0.58) | CYP17A1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10002469 | 0.71 | CYP17A1 (0.44) | CYP17A1LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2775045 | 0.70 | — | — | |
| Carbamic Acid SCHEMBL31175940 | 0.70 | LOXL2 (0.73) | CYP17A1LOXL2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL2673007 | 0.70 | CA2 (0.56) | CYP17A1LOXL2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |