Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981953 | 0.97 | RHOC (0.44) | RHOCRHOAMCL1ALDH1A1NPC1 | |
| SCHEMBL7979391 | 0.94 | RHOC (0.47) | RHOCRHOAMCL1ALDH1A1NPC1 | |
| SCHEMBL7979083 | 0.93 | RHOC (0.44) | RHOCRHOAMCL1ALDH1A1NPC1 | |
| SCHEMBL7976125 | 0.92 | RHOC (0.44) | RHOCRHOAMCL1NPC1TMEM97 | |
| SCHEMBL7979322 | 0.91 | PPARD (0.42) | RHOCRHOAMCL1NPC1TMEM97 | |
| SCHEMBL7976273 | 0.89 | RHOC (0.47) | RHOCRHOAALDH1A1NPC1TMEM97 | |
| SCHEMBL7977739 | 0.89 | RHOC (0.51) | RHOCRHOAALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL7979250 | 0.89 | RHOC (0.48) | RHOCRHOAALDH1A1NPC1TMEM97 | |
| SCHEMBL8060909 | 0.89 | NPC1 (0.52) | RHOCRHOAALDH1A1NPC1HPGD | |
| SCHEMBL7979521 | 0.89 | SCN9A (0.47) | RHOCRHOAALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5952386-A | EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-14 | — | — | US | disclosed |
| WO-1996033160-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-24 | — | — | WO | disclosed |