SCHEMBL7976273

SCHEMBL7976273

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCNC(=O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RHOC P08134 1/20 0.47
RHOA P61586 1/20 0.47
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 1/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
MLYCD O95822 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
TRPV1 Q8NER1 2/20 0.39
TMEM97 Q5BJF2 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
MAPT P10636 2/20 0.39
EPHX2 P34913 1/20 0.39
PPARD Q03181 2/20 0.39
POLB P06746 1/20 0.39
CASP3 P42574 1/20 0.39
SENP7 Q9BQF6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975921 0.97 RHOC (0.44) RHOCRHOAKMT2AL3MBTL1HPGD
SCHEMBL7979083 0.94 RHOC (0.44) RHOCRHOAKMT2AL3MBTL1HPGD
SCHEMBL7979322 0.92 PPARD (0.42) RHOCRHOAKMT2AL3MBTL1HPGD
SCHEMBL7979570 0.89 RHOC (0.47) RHOCRHOAKMT2AL3MBTL1HPGD
SCHEMBL8063136 0.89 NPC1 (0.48) RHOCRHOAKMT2AL3MBTL1HPGD
SCHEMBL7977745 0.89 SCN9A (0.47) RHOCRHOAPPARDPPARG
SCHEMBL7979250 0.88 RHOC (0.48) RHOCRHOAHPGDSMN1; SMN2ALDH1A1
SCHEMBL7977739 0.88 RHOC (0.51) RHOCRHOAKMT2AHPGDSMN1; SMN2
SCHEMBL7979434 0.88 RHOC (0.39) RHOCRHOARAB9ANPC1MRGPRX4
SCHEMBL7982372 0.88 PPARD (0.44) RHOCRHOAPPARDPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
EP-0824514-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-02-25 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed