Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994197 | 0.85 | MAPT (0.38) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL7991696 | 0.81 | — | — | |
| SCHEMBL2967535 | 0.73 | HCAR3 (0.53) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2961182 | 0.70 | HCAR3 (0.49) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL21522808 | 0.69 | HCAR3 (0.48) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL30889005 | 0.69 | HCAR3 (0.48) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL5784069 | 0.67 | MAPT (0.49) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL28763394 | 0.66 | HCAR3 (0.48) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29061680 | 0.66 | HCAR3 (0.58) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10719012 | 0.64 | MAPT (0.38) | MAPTCYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090102-A2 | 6-HETEROCYCLYL-3-OXO-3,4-DIHYDRO-QUINOXALINES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-29 | — | — | WO | disclosed |