Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979573 | 0.85 | MAPT (0.38) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27044907 | 0.75 | MAPT (0.39) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9631118 | 0.72 | PPOX (0.43) | — | |
| SCHEMBL29174352 | 0.68 | MAPT (0.36) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22467860 | 0.68 | MAPT (0.35) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4670199 | 0.67 | TDP1 (0.62) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27044908 | 0.67 | SMN1; SMN2 (0.40) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29847854 | 0.66 | MAPT (0.76) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16513593 | 0.66 | MAPT (0.76) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9054575 | 0.65 | ALDH1A1 (0.32) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090102-A2 | 6-HETEROCYCLYL-3-OXO-3,4-DIHYDRO-QUINOXALINES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-29 | — | — | WO | disclosed |