Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979588 | 0.77 | MGLL (0.60) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL27267653 | 0.75 | KMT2A (0.56) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL1028065 | 0.74 | MAPT (0.62) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL95791 | 0.74 | KMT2A (0.58) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL632993 | 0.74 | KMT2A (0.58) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL95792 | 0.74 | KMT2A (0.58) | KDM4EMAPTRAB9ANPC1KMT2A | |
| Hydrochloric Acid SCHEMBL5008268 | 0.73 | MAPT (0.61) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL23094304 | 0.73 | MAPT (0.67) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL19900671 | 0.73 | KMT2A (0.78) | KDM4EMAPTRAB9ANPC1KMT2A | |
| SCHEMBL14270154 | 0.73 | KMT2A (0.53) | KDM4EMAPTRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |