Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17335700 | 0.83 | MGLL (0.57) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL19888952 | 0.82 | MGLL (0.56) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL12573089 | 0.80 | MGLL (0.52) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL6679842 | 0.77 | MGLL (0.54) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL7979585 | 0.77 | KDM4E (0.51) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL13202619 | 0.76 | KMT2A (0.58) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL10134061 | 0.76 | PTPN1 (0.54) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL27267653 | 0.75 | KMT2A (0.56) | MGLLPTPN1KMT2AMAPTPOLB | |
| SCHEMBL1028065 | 0.74 | MAPT (0.62) | PTPN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL4919768 | 0.74 | ESRRG (0.53) | MGLLPTPN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1478084-A | Compounds useful in treatment of inflammatory diseases | — | 2004-02-25 | — | — | CN | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |