Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975847 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL6042179 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL30098391 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL7810699 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL12895756 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL104391 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL6328368 | 0.78 | ALDH1A1 (0.67) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL1250902 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL7977048 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 | |
| SCHEMBL7977046 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2RAB9AALDH1A1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |