Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328368 | 0.89 | ALDH1A1 (0.67) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL7977046 | 0.88 | ALDH1A1 (0.66) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL3046287 | 0.83 | L3MBTL1 (0.62) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL3045660 | 0.82 | L3MBTL1 (0.64) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL6388291 | 0.81 | ATM (0.88) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL14622721 | 0.79 | L3MBTL1 (0.58) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL16975847 | 0.78 | SMN1; SMN2 (0.61) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL6331512 | 0.78 | LMNA (0.58) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL7979609 | 0.77 | SMN1; SMN2 (0.60) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 | |
| SCHEMBL6042179 | 0.77 | SMN1; SMN2 (0.60) | ALDH1A1GAAL3MBTL1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |