Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12022268 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2APOLBHTR6 | |
| SCHEMBL21592980 | 0.88 | MCHR1 (0.42) | ALDH1A1 | |
| SCHEMBL967140 | 0.82 | — | — | |
| SCHEMBL805270 | 0.81 | LMNA (0.51) | ALDH1A1LMNAKMT2APOLBBRD4 | |
| SCHEMBL8282498 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2APOLBHTR6 | |
| SCHEMBL967805 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL27330745 | 0.80 | — | — | |
| SCHEMBL19502747 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAKMT2APOLBHTR6 | |
| SCHEMBL19668292 | 0.80 | KMT2A (0.45) | ALDH1A1LMNAKMT2APOLBL3MBTL1 | |
| SCHEMBL1559228 | 0.79 | LMNA (0.47) | ALDH1A1LMNAKMT2APOLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |