Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962093 | 0.78 | CTSA (0.32) | FDPS | |
| SCHEMBL3014948 | 0.76 | CHRM2 (0.40) | FDPSSLC6A3ACACBALDH1A1PKM | |
| SCHEMBL2039866 | 0.74 | FDPS (0.51) | FDPSSLC6A3ACACBALDH1A1PKM | |
| SCHEMBL2035542 | 0.73 | — | — | |
| SCHEMBL30561243 | 0.73 | LTA4H (0.34) | FDPSSLC6A3ALDH1A1PKM | |
| SCHEMBL38661401 | 0.73 | FDPS (0.33) | FDPSSLC6A3ALDH1A1PKM | |
| SCHEMBL38663161 | 0.73 | FDPS (0.33) | FDPSSLC6A3ALDH1A1PKM | |
| SCHEMBL4420207 | 0.73 | MAPK1 (0.32) | — | |
| SCHEMBL7969323 | 0.72 | PTPRA (0.44) | FDPSPKM | |
| SCHEMBL2033995 | 0.72 | FDPS (0.53) | FDPSSLC6A3ACACBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |