Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311829 | 0.90 | TP53 (0.42) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL10359458 | 0.90 | TP53 (0.42) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL10359421 | 0.88 | DNM1 (0.44) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL7909313 | 0.88 | DNM1 (0.44) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL11121824 | 0.85 | CYP2C9 (0.44) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL7901288 | 0.85 | CYP2C9 (0.59) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL7901285 | 0.85 | CYP2C9 (0.59) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL11123619 | 0.83 | TSHR (0.47) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL5845493 | 0.83 | THRB (0.46) | THRBCYP2C9MAPTMEN1KMT2A | |
| SCHEMBL7901291 | 0.82 | DNM1 (0.47) | THRBCYP2C9MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291544-B1 | STORAGE STABILITY; FOR BONDING METALS, PLASTICS, RUBBERS, GLASS, WOOD, PAPER, LIVE, SOFT OR BONE TISSUE | CHEMENCE, INC. | 2001-09-18 | — | — | US | disclosed |