Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDH1 | P12830 | 1/20 | 0.40 |
| ▸ | APC | P25054 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893558 | 0.84 | LCK (0.53) | LCKBTKCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7979858 | 0.84 | LCK (0.53) | LCKBTKCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7987206 | 0.75 | LCK (0.65) | LCK | |
| SCHEMBL29893312 | 0.75 | RXRA (0.38) | LCKCSNK2A2CSNK2BCSNK2A1HSD17B10 | |
| SCHEMBL7983772 | 0.75 | LCK (0.84) | LCK | |
| SCHEMBL29892899 | 0.74 | KDM4E (0.43) | LCKCSNK2A2CSNK2BHSD17B10HCAR3 | |
| SCHEMBL31136680 | 0.74 | LCK (0.63) | LCKBTKCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31040881 | 0.72 | FGFR1 (0.42) | LCKBTKCSNK2A2CSNK2BCSNK2A1 | |
| Hydrochloric Acid SCHEMBL31137004 | 0.71 | FGFR1 (0.41) | LCKBTKCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10643646 | 0.70 | TDP1 (0.67) | HTTSMN1; SMN2L3MBTL1CDH1APC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |