Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983412 | 0.85 | LCK (0.48) | LCKPTPN1PTPN2SMN1; SMN2GABRA1 | |
| SCHEMBL31137271 | 0.81 | LCK (0.54) | LCKPTPN1PTPN2GABRA1GABRA5 | |
| SCHEMBL7987230 | 0.77 | LCK (1.00) | LCKKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11090333 | 0.76 | ALDH1A1 (0.42) | LCKSMN1; SMN2TYMSKDM4EALDH1A1 | |
| SCHEMBL11082707 | 0.75 | GABRA1 (0.51) | SMN1; SMN2GABRA1GABRA5KDM4EALDH1A1 | |
| SCHEMBL7987544 | 0.74 | LCK (0.73) | LCK | |
| SCHEMBL31137531 | 0.73 | LCK (0.39) | LCKPTPN1KDM4EALDH1A1GLA | |
| SCHEMBL7983721 | 0.73 | LCK (0.66) | LCKKMT2ARAB9ANPC1 | |
| SCHEMBL31554053 | 0.72 | LCK (0.48) | LCKSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL9773340 | 0.70 | PTPN2 (0.46) | LCKPTPN1PTPN2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |