Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 6/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979963 | 1.00 | PTAFR (0.47) | PTAFRMMP12LMNAECE1POLB | |
| SCHEMBL7978380 | 0.92 | LMNA (0.46) | PTAFRMMP12LMNAECE1POLB | |
| SCHEMBL7978383 | 0.92 | LMNA (0.46) | PTAFRMMP12LMNAECE1POLB | |
| SCHEMBL7980076 | 0.87 | PTAFR (0.51) | PTAFRLMNAPOLBHPGDHTT | |
| SCHEMBL7966272 | 0.87 | PTAFR (0.45) | PTAFRPOLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7980074 | 0.87 | PTAFR (0.51) | PTAFRLMNAPOLBHPGDHTT | |
| SCHEMBL7966267 | 0.87 | PTAFR (0.45) | PTAFRPOLBHPGDHTTSMN1; SMN2 | |
| SCHEMBL7976720 | 0.85 | KCNK3 (0.43) | PTAFRMMP12LMNAPOLBHPGD | |
| SCHEMBL7976718 | 0.85 | KCNK3 (0.43) | PTAFRMMP12LMNAPOLBHPGD | |
| SCHEMBL7976785 | 0.85 | ECE1 (0.48) | PTAFRMMP12LMNAECE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | claimed |
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |