Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980094 | 1.00 | DYRK1A (0.51) | DYRK1ATP53RGS12PABPC1MAPT | |
| SCHEMBL7128690 | 0.87 | DYRK1A (0.40) | DYRK1ATP53MAPTGAAGSK3B | |
| SCHEMBL7128685 | 0.87 | DYRK1A (0.40) | DYRK1ATP53MAPTGAAGSK3B | |
| SCHEMBL7117409 | 0.78 | DYRK1A (0.41) | DYRK1ATP53MAPTGAAGSK3B | |
| SCHEMBL7117407 | 0.78 | DYRK1A (0.41) | DYRK1ATP53MAPTGAAGSK3B | |
| SCHEMBL7984129 | 0.75 | FGFR3 (0.42) | DYRK1AGSK3BFGFR3KDRFYN | |
| SCHEMBL7121296 | 0.75 | CYP1A2 (0.50) | DYRK1AGSK3BFGFR3KDRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7123999 | 0.74 | FGFR3 (0.41) | DYRK1AGSK3BFGFR3KDRFYN | |
| SCHEMBL7120271 | 0.73 | DYRK1A (0.51) | DYRK1ATP53RGS12PABPC1GAA | |
| SCHEMBL7121293 | 0.73 | FYN (0.40) | DYRK1AGSK3BFGFR3KDRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |