Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 8/20 | 0.41 |
| ▸ | WNT1 | P04628 | 3/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7123999 | 0.99 | FGFR3 (0.41) | FGFR3KDRDYRK1ADYRK3CCNT1 | |
| SCHEMBL7121296 | 0.87 | CYP1A2 (0.50) | FGFR3KDRDYRK1AFYNGSK3B | |
| SCHEMBL6808846 | 0.76 | MAPT (0.63) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL7980096 | 0.75 | DYRK1A (0.51) | FGFR3KDRDYRK1AFYNGSK3B | |
| SCHEMBL7980094 | 0.75 | DYRK1A (0.51) | FGFR3KDRDYRK1AFYNGSK3B | |
| SCHEMBL6754326 | 0.74 | MAP4K4 (0.49) | DYRK1ADYRK3CCNT1CCNA2CDK2 | |
| SCHEMBL6756716 | 0.74 | FYN (0.54) | DYRK1ACCNT1CDK9FYNGSK3B | |
| SCHEMBL7125139 | 0.73 | ALDH1A1 (0.57) | — | |
| SCHEMBL6754365 | 0.73 | DYRK1A (0.52) | DYRK1AGSK3B | |
| SCHEMBL6804499 | 0.73 | ESRRG (0.59) | DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |