Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27471544 | 0.98 | KDM4E (0.96) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| Trimethylammonium SCHEMBL27855504 | 0.93 | KDM4E (0.86) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| Piperazine SCHEMBL25235944 | 0.89 | KDM4E (0.80) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6476396 | 0.89 | KDM4E (0.79) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL27933369 | 0.87 | KDM4E (0.77) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1600584 | 0.86 | KDM4E (0.76) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| Piperidine SCHEMBL29006137 | 0.85 | KDM4E (0.73) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL30393282 | 0.85 | KDM4E (0.82) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1276481 | 0.85 | KDM4E (0.82) | KDM4EGAAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11291466 | 0.85 | NPC1 (0.79) | KDM4EGAAALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079303-B1 | NAPHTHYLUREA COMPOUND FOR TREATING CORNEAL NEOVASCULAR DISEASE | SUZHOU RAYMON PHARMACEUTICALS COMPANY LTD (CN) | 2026-02-04 | — | — | EP | claimed |
| EP-4635495-A1 | USE OF NAPHTHYLUREA COMPOUNDS IN PREPARATION OF DRUGS FOR TREATING PTERYGIUM | Suzhou Raymon Pharmaceuticals Company, Ltd. (CN) | 2025-10-22 | — | — | EP | claimed |
| US-12440480-B2 | Use of naphthylurea compound | SUZHOU RAYMON PHARMACEUTICALS COMPANY, LTD. (CN) | 2025-10-14 | — | — | US | claimed |
| CN-119859278-A | Naphthizimide modified magnetic nanoparticle for iron ion fluorescence detection and preparation method thereof | 江苏海洋大学 | 2025-04-22 | — | — | CN | claimed |
| CN-116178248-B | Naphthyl urea-piperidine compounds, and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2024124411-A1 | USE OF NAPHTHYLUREA COMPOUNDS IN PREPARATION OF DRUGS FOR TREATING PTERYGIUM | 苏州锐明新药研发有限公司 | 2024-06-20 | — | — | WO | claimed |
| CN-116731551-B | Environment-friendly paint remover for aviation use and preparation method and application thereof | 广东润和新材料科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| EP-4373520-A1 | COMPOSITIONS AND VACCINES FOR TREATING AND/OR PREVENTING CORONAVIRUS VARIANT INFECTIONS AND METHODS OF USING THE SAME | EnGeneIC Molecular Delivery Pty Ltd. (AU) | 2024-05-29 | — | — | EP | claimed |
| CN-118065173-A | Temperature regulating auxiliary agent for double-color erasable thermosensitive paper, and preparation method and application thereof | 湖南鼎一致远科技发展股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117263851-A | Pyridine-naphthyl urea-piperazine derivative, and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| WO-1991012009-A1 | USE OF SURAMIN TO TREAT RHEUMATOLOGIC DISEASES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1991-08-22 | — | — | WO | claimed |
| US-4692400-A | CONTAINING A UREIDO- AND ACYLAMINO-CONTAINING PHENOL-TYPE CYAN COUPLER AND NEGATIVE-TYPE CORESHELL SILVER HALIDE GRAINS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-09-08 | — | — | US | claimed |
| EP-0102821-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1987-04-08 | — | — | EP | claimed |
| EP-0204416-A2 | Light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1986-12-10 | — | — | EP | claimed |
| EP-0201027-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1986-11-12 | — | — | EP | claimed |
| US-4594314-A | Containing phenol-type cyan coupler | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1986-06-10 | — | — | US | claimed |
| EP-0102821-A1 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1984-03-14 | — | — | EP | claimed |
| US-4292238-A | Alkylation of benzthiazole-azo-phenylamine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | claimed |
| US-4021428-A | 4-Piperidino-5-oxo-2-pyrazolines | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | claimed |
| US-3956339-A | 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12440480-B2 | Use of naphthylurea compound | UACA, CRYAA, VEGFA | KDM4E 4231/4885GAA 394/4885ALDH1A1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.