Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333220 | 0.81 | L3MBTL1 (0.40) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11478684 | 0.76 | MEN1 (0.40) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7981240 | 0.76 | KMT2A (0.48) | KDM4EGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6260533 | 0.74 | GAA (0.47) | KDM4EGAACYP1A2CYP3A4L3MBTL1 | |
| SCHEMBL6258693 | 0.71 | CYP3A4 (0.47) | KDM4EGAACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3531433 | 0.69 | GCK (0.52) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5649334 | 0.69 | MEN1 (0.40) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11764095 | 0.69 | GAA (0.41) | KDM4EGAAL3MBTL1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL5649176 | 0.68 | MEN1 (0.40) | GAACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11626476 | 0.68 | KDM4E (0.40) | KDM4EGAACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |