SCHEMBL7980283

SCHEMBL7980283

CCCCO[Si](C)(C)CCl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28789178 0.93 TSHR (0.36) TSHRTDP1ALDH1A1CA1CA2
SCHEMBL4076539 0.84
SCHEMBL12660046 0.81
SCHEMBL8538734 0.80 TSHR (0.37) ADRB2ADRB1ADRB3TSHRTDP1
SCHEMBL17937858 0.79 TSHR (0.42) ADRB2ADRB1ADRB3TSHRTDP1
SCHEMBL705135 0.79 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL4281440 0.79 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL705516 0.79 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL15292867 0.77 ADRB2 (0.38) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL12660057 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230963-A Oil-resistant high-impact ABS/PBT composite material and preparation method thereof 湖州伟悦高分子材料有限公司 2022-03-25 CN claimed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US claimed
CN-114230963-B Oil-resistant high-impact ABS/PBT composite material and preparation method thereof 湖州伟悦高分子材料有限公司 2022-06-14 CN disclosed
CN-114230963-A Oil-resistant high-impact ABS/PBT composite material and preparation method thereof 湖州伟悦高分子材料有限公司 2022-03-25 CN disclosed
US-6277902-B1 RUBBER COMPOUNDS COMPRISING SOLUBLE RUBBER, HYDROPHOBIZED FILLER HAVING SPECIFIED METHANOL WETTABILITY, SUPPORTEDPOLYSULFIDIC-SILANE COMPOUNDS PREPARED BY REACTION OF HALOALKYLSILANES, ORGANIC HALOGEN COMPOUNDS AND POLYSULFIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-08-21 US disclosed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US disclosed
US-5770754-A Method of preparing polysulphidic silyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1998-06-23 US disclosed