Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005296 | 0.84 | — | — | |
| SCHEMBL7980283 | 0.80 | ADRB2 (0.36) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL7760596 | 0.79 | TSHR (0.42) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL703586 | 0.79 | ADRB2 (0.39) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL4277959 | 0.79 | ADRB2 (0.39) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL703594 | 0.79 | ADRB2 (0.39) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL706695 | 0.77 | ADRB2 (0.38) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL705364 | 0.77 | ADRB2 (0.38) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL1595849 | 0.77 | ADRB2 (0.38) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL4090916 | 0.77 | ADRB2 (0.38) | TSHRADRB2ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770754-A | Method of preparing polysulphidic silyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-23 | — | — | US | disclosed |
| US-4366184-A | PLASMA/GASES/, ORGANOSILICON COMPOUND | LORD CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |