Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980360 | 1.00 | LMNA (0.30) | LMNA | |
| SCHEMBL7978715 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7980475 | 0.76 | — | — | |
| SCHEMBL5725727 | 0.67 | NPC1 (0.33) | — | |
| SCHEMBL29129386 | 0.61 | — | — | |
| SCHEMBL5725154 | 0.61 | LMNA (0.34) | LMNA | |
| SCHEMBL5725158 | 0.61 | LMNA (0.34) | LMNA | |
| SCHEMBL7977043 | 0.60 | RAB9A (0.32) | LMNA | |
| SCHEMBL9077266 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL11490460 | 0.59 | LMNA (0.57) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174909-B1 | FOR TREATING ANALGESIA, PSYCHOSIS, CONVULSIONS, EPILEPSY, ANXIETY, MUSCULAR AND MOVEMENT DISORDERS, SPASTIC DISORDERS OR SYMPTOMS OF HUNTINGTON'S OR PARKINSONS DISEASE | H. LUNDBECK A/S (DK) | 2001-01-16 | — | — | US | disclosed |
| US-5998613-A | PSYCHOLOGICAL DISORDERS; ANALGESICS; ANTICONVULSANTS | H. LUNDBECK A/S (DK) | 1999-12-07 | — | — | US | disclosed |