Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 5/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836651 | 0.90 | POLB (0.36) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7979984 | 0.90 | POLB (0.36) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7822919 | 0.90 | POLB (0.36) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7822922 | 0.90 | POLB (0.36) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7966090 | 0.87 | POLB (0.34) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7966092 | 0.87 | POLB (0.34) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7982592 | 0.87 | POLB (0.35) | POLBHPGDHTTSMN1; SMN2PTAFR | |
| SCHEMBL7766502 | 0.80 | MEN1 (0.37) | POLBSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL7771572 | 0.80 | MEN1 (0.37) | POLBSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL7833545 | 0.78 | CHRNA7 (0.39) | L3MBTL1NPC1RAB9ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |