Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957875 | 0.83 | TAS1R3 (0.46) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL417252 | 0.83 | SLC6A4 (0.51) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL12000676 | 0.81 | TACR1 (0.48) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL6449473 | 0.80 | POLB (0.44) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL21600828 | 0.79 | ATM (0.45) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL22957772 | 0.79 | HTT (0.51) | ALDH1A1MAPTGAATAS1R3TAS1R1 | |
| SCHEMBL5067489 | 0.79 | ALDH1A1 (0.96) | ALDH1A1MAPTGAAACHETSHR | |
| SCHEMBL855754 | 0.79 | IRAK4 (0.47) | ALDH1A1TAS1R3TAS1R1TACR1IRAK4 | |
| SCHEMBL29786441 | 0.79 | IRAK4 (0.47) | ALDH1A1TAS1R3TAS1R1TACR1IRAK4 | |
| SCHEMBL5547142 | 0.77 | TAS1R3 (0.45) | ALDH1A1MAPTTAS1R3TAS1R1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255318-B1 | CYTOMEGLO VIRUS | BIOCHEM PHARMA INC. (CA) | 2001-07-03 | — | — | US | claimed |