Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 11/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981209 | 0.94 | PDPK1 (0.41) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL2574496 | 0.93 | KDM4E (0.45) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL2574497 | 0.93 | KDM4E (0.45) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL7225272 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL23252178 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1LMNAACHEBCHE | |
| SCHEMBL6979863 | 0.90 | ACHE (0.44) | ACHEBCHE | |
| SCHEMBL6979865 | 0.90 | ACHE (0.44) | ACHEBCHE | |
| SCHEMBL8186890 | 0.89 | MEN1 (0.46) | ALDH1A1MEN1KMT2AACHEBCHE | |
| SCHEMBL6977153 | 0.89 | ACHE (0.43) | ACHEBCHE | |
| SCHEMBL6977152 | 0.89 | ACHE (0.43) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |