Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980392 | 0.94 | SMN1; SMN2 (0.39) | PDE5ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7978890 | 0.90 | SMN1; SMN2 (0.40) | PDE5ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7966922 | 0.87 | L3MBTL1 (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL7983018 | 0.87 | USP2 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL7980615 | 0.86 | PDE5A (0.39) | PDE5ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7980691 | 0.84 | MAPK1 (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL194662 | 0.81 | USP2 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL7966908 | 0.81 | MEN1 (0.38) | PDE5ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7966894 | 0.81 | SMN1; SMN2 (0.39) | PDE5ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7691943 | 0.74 | PARG (0.36) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213373-A | Pyrimidin-4-one-derivatives as pesticide | NOVARTIS AG (CH) | 1999-04-07 | — | — | CN | claimed |
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | claimed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | claimed |
| US-6262058-B1 | Pyrimidin-4-one derivatives as pesticide | SYNGENTA CROP PROTECTION, INC. | 2001-07-17 | — | — | US | disclosed |
| CN-1213373-A | Pyrimidin-4-one-derivatives as pesticide | NOVARTIS AG (CH) | 1999-04-07 | — | — | CN | disclosed |