Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980392 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9APDE5AALDH1A1 | |
| SCHEMBL7980723 | 0.90 | PDE5A (0.39) | SMN1; SMN2NPC1RAB9APDE5AALDH1A1 | |
| SCHEMBL7977486 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9APDE5AALDH1A1 | |
| SCHEMBL7966908 | 0.81 | MEN1 (0.38) | SMN1; SMN2NPC1RAB9APDE5AALDH1A1 | |
| SCHEMBL194662 | 0.77 | USP2 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL7966894 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9APDE5AALDH1A1 | |
| SCHEMBL7966922 | 0.76 | L3MBTL1 (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL7980615 | 0.75 | PDE5A (0.39) | SMN1; SMN2NPC1RAB9APDE5AALDH1A1 | |
| SCHEMBL7667264 | 0.71 | PARG (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL7670733 | 0.71 | ADORA1 (0.34) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | claimed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | claimed |
| US-6262058-B1 | Pyrimidin-4-one derivatives as pesticide | SYNGENTA CROP PROTECTION, INC. | 2001-07-17 | — | — | US | disclosed |
| EP-0888359-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | Novartis AG (CH) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997033890-A1 | PYRIMIDIN-4-ONE DERIVATIVES AS PESTICIDE | NOVARTIS AG (CH) | 1997-09-18 | — | — | WO | disclosed |