Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983826 | 0.92 | POLB (0.44) | POLBMMP13MMP1MMP9MMP2 | |
| SCHEMBL7984108 | 0.86 | KAT6A (0.50) | POLBACACBALDH1A1KAT6AL3MBTL1 | |
| SCHEMBL7984111 | 0.86 | KAT6A (0.50) | POLBACACBALDH1A1KAT6AL3MBTL1 | |
| SCHEMBL7983907 | 0.82 | KAT6A (0.49) | POLBALDH1A1KAT6AL3MBTL1KMT2A | |
| SCHEMBL7983911 | 0.82 | KAT6A (0.49) | POLBALDH1A1KAT6AL3MBTL1KMT2A | |
| SCHEMBL7982468 | 0.80 | EGFR (0.43) | MMP13MMP1MMP9ALDH1A1L3MBTL1 | |
| SCHEMBL7981503 | 0.76 | EGFR (0.43) | MMP13MMP1MMP9MMP2ALDH1A1 | |
| SCHEMBL7983169 | 0.73 | KAT6A (0.37) | POLBACACBRAPGEF3ALDH1A1KAT6A | |
| SCHEMBL7980773 | 0.73 | F2 (0.55) | POLBKMT2AF2 | |
| SCHEMBL14675766 | 0.73 | L3MBTL1 (0.57) | ALDH1A1KAT6AL3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | claimed |