SCHEMBL7983169

SCHEMBL7983169

CC(Cc1ccccc1OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 7/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 3/20 0.36
ACACB O00763 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.35
SLC16A3 O15427 1/20 0.35
ALOX12 P18054 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RAPGEF3 O95398 1/20 0.35
F2 P00734 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7983826 0.77 POLB (0.44) KAT6AKMT2AALDH1A1ACACBLMNA
SCHEMBL7980778 0.73 POLB (0.44) KAT6AKMT2AALDH1A1ACACBLMNA
SCHEMBL7984108 0.71 KAT6A (0.50) KAT6AMEN1KMT2AALDH1A1ACACB
SCHEMBL7984111 0.71 KAT6A (0.50) KAT6AMEN1KMT2AALDH1A1ACACB
SCHEMBL7595064 0.70 CXCL8 (0.47) L3MBTL1
SCHEMBL7983165 0.69 F2 (0.52) MEN1KMT2AF2
SCHEMBL7983907 0.68 KAT6A (0.49) KAT6AMEN1KMT2AALDH1A1POLB
SCHEMBL7983911 0.68 KAT6A (0.49) KAT6AMEN1KMT2AALDH1A1POLB
SCHEMBL14675766 0.68 L3MBTL1 (0.57) KAT6AMEN1KMT2AALDH1A1LMNA
SCHEMBL31299567 0.67 CA1 (0.53) MEN1KMT2ALMNAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US claimed