Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 6/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690708 | 0.81 | L3MBTL1 (0.42) | L3MBTL1ELANEPLCG1FAPRAB9A | |
| SCHEMBL7969446 | 0.81 | ESR1 (0.44) | ELANEFAP | |
| SCHEMBL7979469 | 0.81 | ESR1 (0.44) | ELANEFAP | |
| SCHEMBL9216219 | 0.81 | ELANE (0.46) | L3MBTL1ELANEPLCG1FAPHTT | |
| SCHEMBL10612514 | 0.81 | ELANE (0.46) | L3MBTL1ELANEPLCG1FAPHTT | |
| SCHEMBL9216222 | 0.81 | ELANE (0.46) | L3MBTL1ELANEPLCG1FAPHTT | |
| SCHEMBL9026059 | 0.79 | ELANE (0.39) | L3MBTL1ELANEPLCG1FAPHTT | |
| SCHEMBL10757697 | 0.79 | ELANE (0.42) | L3MBTL1ELANEPLCG1FAPHTT | |
| SCHEMBL10757699 | 0.79 | ELANE (0.42) | L3MBTL1ELANEPLCG1FAPHTT | |
| SCHEMBL10757693 | 0.79 | ELANE (0.42) | L3MBTL1ELANEPLCG1FAPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174877-B1 | EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-16 | — | — | US | disclosed |