Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 6/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | PLAT | P00750 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGAV | P06756 | 8/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | KLK8 | O60259 | 2/20 | 0.44 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | KLK2 | P20151 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | PROC | P04070 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983022 | 0.92 | ITGB3 (0.42) | PLGF2PLAUPLATITGB3 | |
| SCHEMBL7983016 | 0.92 | ITGB3 (0.42) | PLGF2PLAUPLATITGB3 | |
| SCHEMBL7445939 | 0.86 | ITGB3 (0.45) | ITGB3ITGAVITGA2BIDO1TDO2 | |
| SCHEMBL7216598 | 0.80 | ITGB3 (0.42) | ITGB3ITGAVITGA2BIDO1TDO2 | |
| SCHEMBL7983187 | 0.80 | ITGB3 (0.44) | PLGF2PLAUPLATITGB3 | |
| Hydrochloric Acid SCHEMBL8492406 | 0.79 | ITGB3 (0.44) | PLGF2PLAUPLATITGB3 | |
| SCHEMBL7445928 | 0.79 | ITGB3 (0.71) | PLGF2PLAUPLATITGB3 | |
| SCHEMBL7980899 | 0.79 | ITGB3 (0.71) | PLGF2PLAUPLATITGB3 | |
| SCHEMBL7449328 | 0.78 | ITGB3 (0.40) | ITGB3ITGAVITGA2BPPARAIDO1 | |
| SCHEMBL7211331 | 0.76 | ITGB3 (0.66) | ITGB3ITGAVITGA2BIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191282-B1 | DERIVATIVES OF 5-MEMBERED NITROGEN CONTAINING HETEROCYCLIC RING IS USED AS ANTICARCINOGENIC AGENT AND ANTICOAGULANT | HOECHST MARION ROUSSEL (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5981492-A | ADMINISTERED TO THE PATIENT TO INHIBIT THROMBOCYTE AGGREGATION, THE METASTASIZATION OF CARCINOMA CELLS, THE BINDING OF OSTEOCLASTS TO THE BONE SURFACE, OR FOR THE TREATMENT OF THROMBOSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |