Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980962 | 0.85 | ALDH1A1 (0.43) | KDM4EUSP2ALDH1A1TSHRKMT2A | |
| SCHEMBL27677668 | 0.78 | PPARA (0.42) | ALDH1A1KMT2AMEN1MAPK1MAPT | |
| SCHEMBL7980960 | 0.67 | KDM4E (0.39) | KDM4EUSP2ALDH1A1TSHRKMT2A | |
| SCHEMBL10072233 | 0.66 | HCAR2 (0.64) | USP2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9720573 | 0.64 | PPARA (0.46) | KDM4EALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7981965 | 0.63 | MAPT (0.37) | KDM4EUSP2ALDH1A1TSHRKMT2A | |
| SCHEMBL17290815 | 0.62 | KMT2A (0.38) | KDM4EALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6812056 | 0.62 | KMT2A (0.51) | ALDH1A1KMT2AMEN1MAPTPPARA | |
| SCHEMBL28135125 | 0.62 | MAPT (0.41) | ALDH1A1TSHRKMT2AMEN1MAPK1 | |
| SCHEMBL17826360 | 0.61 | PPARA (0.44) | KDM4EALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245716-B1 | LOW DOSAGE; NONPHYTOTOXIC | NIPPON SODA CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |