Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877603 | 0.82 | POLB (0.53) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL875841 | 0.82 | MAPK1 (0.58) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL15746491 | 0.82 | DDB1 (0.51) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL4501819 | 0.82 | KMT2A (0.44) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL4491902 | 0.82 | KMT2A (0.44) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL873535 | 0.82 | DDB1 (0.51) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL872472 | 0.82 | DDB1 (0.55) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL15933035 | 0.80 | ALDH1A1 (0.44) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL31708217 | 0.80 | HSD17B10 (0.44) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL5569137 | 0.78 | KMT2A (0.42) | MAPK1KMT2AALDH1A1CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001096326-A1 | ALPHA-PHENYLSULPHINYL-ALPHA-HALOGENO-BUTYROLACTONE AND HALOGENO-2-BUTEN-2-OLIDE-4 COMPOUNDS USEFUL FOR PREPARING HALOGENO-2-OXYMETHYL-4-FURANONE(4H) | PPG-SIPSY (SCA) (FR) | 2001-12-20 | — | — | WO | disclosed |