Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390088 | 0.87 | ATM (0.51) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL27801903 | 0.83 | AKR1C3 (0.55) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL7976506 | 0.82 | SMN1; SMN2 (0.47) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL2698568 | 0.81 | ALDH1A1 (0.58) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL30155394 | 0.81 | ALDH1A1 (0.58) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL2438044 | 0.81 | GRM8 (0.50) | GRM8GRM6GRM4ALDH1A1HIF1A | |
| SCHEMBL20576274 | 0.80 | GRM8 (0.52) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL29975742 | 0.79 | GRM8 (0.57) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL21853759 | 0.79 | GRM8 (0.57) | GRM8GRM6GRM4VCAM1ALDH1A1 | |
| SCHEMBL21853758 | 0.79 | GRM8 (0.57) | GRM8GRM6GRM4VCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457153-B | Industrial preparation method of 2,4, 5-trifluoro-phenylacetic acid | 台州臻挚生物科技有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-112457153-A | Industrial preparation method of 2,4, 5-trifluoro-phenylacetic acid | 杭州臻挚生物科技有限公司 | 2021-03-09 | — | — | CN | claimed |
| WO-2023186881-A1 | P38 MAP KINASE INHIBITORS FOR USE IN THE TREATMENT OF COLORECTAL CANCER | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2023-10-05 | — | — | WO | disclosed |
| CN-112457153-B | Industrial preparation method of 2,4, 5-trifluoro-phenylacetic acid | 台州臻挚生物科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-112457153-A | Industrial preparation method of 2,4, 5-trifluoro-phenylacetic acid | 杭州臻挚生物科技有限公司 | 2021-03-09 | — | — | CN | disclosed |
| WO-2001055138-A1 | AZOLE DERIVATIVES, THEIR PREPARATION AND USE | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |