Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965004 | 0.86 | GRM8 (0.48) | SMN1; SMN2VCAM1ALDH1A1HIF1AGAA | |
| SCHEMBL14797548 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2VCAM1ALDH1A1HIF1AGAA | |
| SCHEMBL7976616 | 0.86 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1GAALMNAKMT2A | |
| SCHEMBL7976515 | 0.84 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7975219 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2VCAM1ALDH1A1HIF1AGAA | |
| SCHEMBL2432560 | 0.83 | GPR35 (0.45) | SMN1; SMN2VCAM1ALDH1A1HIF1ALMNA | |
| SCHEMBL7981057 | 0.82 | GRM8 (0.52) | SMN1; SMN2VCAM1ALDH1A1HIF1AGAA | |
| SCHEMBL4507232 | 0.80 | CES2 (0.45) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18111369 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2VCAM1ALDH1A1HIF1AGAA | |
| SCHEMBL7383304 | 0.77 | ALDH1A1 (0.51) | SMN1; SMN2VCAM1ALDH1A1HIF1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055138-A1 | AZOLE DERIVATIVES, THEIR PREPARATION AND USE | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |