Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984282 | 0.70 | MAPK1 (0.53) | CYP1A2CYP3A4CLK4HSD17B10CYP2C9 | |
| SCHEMBL31649377 | 0.67 | KDM4E (0.56) | ACHECYP1A2CYP3A4CLK4HSD17B10 | |
| SCHEMBL3209937 | 0.66 | PRNP (0.54) | PRNPRXFP1NPSR1AURKAAURKB | |
| SCHEMBL4859938 | 0.64 | RAD52 (0.69) | ACHEBCHENPSR1AURKAAURKB | |
| SCHEMBL4866244 | 0.63 | MAPK1 (0.59) | ACHEBCHEKMT2AALDH1A1MAPK1 | |
| SCHEMBL13797204 | 0.62 | CTNNB1 (0.86) | CTNNB1TCF7L2 | |
| SCHEMBL16571758 | 0.62 | MGAM (0.56) | CYP1A2CYP2C9TP53PRNPRXFP1 | |
| SCHEMBL4864862 | 0.62 | APP (0.68) | ACHEBCHEL3MBTL1KMT2AMAPK1 | |
| SCHEMBL4532312 | 0.61 | APP (0.67) | CYP1A2CYP3A4CLK4HSD17B10CYP2C9 | |
| SCHEMBL13458341 | 0.61 | KDM4E (0.59) | ACHECYP1A2CYP3A4CLK4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |