Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | USP1 | O94782 | 1/20 | 0.45 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979804 | 0.81 | L3MBTL1 (0.56) | MAPK1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL31649377 | 0.75 | KDM4E (0.56) | MAPK1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL4859938 | 0.71 | RAD52 (0.69) | MAPK1MEN1KMT2AALDH1A1AURKA | |
| SCHEMBL13159064 | 0.70 | ALDH1A1 (0.53) | MAPK1KMT2AALDH1A1MERTK | |
| SCHEMBL7981179 | 0.70 | ACHE (0.43) | MAPK1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL4864862 | 0.69 | APP (0.68) | MAPK1KMT2AL3MBTL1LMNAKDM4E | |
| SCHEMBL854445 | 0.68 | TSHR (0.59) | MEN1KMT2AL3MBTL1MAPTKDM1A | |
| SCHEMBL13458341 | 0.68 | KDM4E (0.59) | MAPK1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL30092903 | 0.68 | ACHE (0.77) | MAPK1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL21567312 | 0.68 | ACHE (0.77) | MAPK1CYP1A2CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |