Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557075 | 0.91 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9444180 | 0.84 | CHRM2 (0.31) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2556850 | 0.77 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8523645 | 0.76 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL206768 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL4198612 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9050123 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14351404 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24663500 | 0.75 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3318136 | 0.75 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |
| EP-0366304-B1 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1998-04-15 | — | — | EP | disclosed |
| EP-0338723-B1 | NOVEL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1993-08-04 | — | — | EP | disclosed |
| US-5217975-A | AZABICYCLIC COMPOUNDS FOR TREATING DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1993-06-08 | — | — | US | disclosed |
| US-5166357-A | Nitrogen heterocylic compounds used in treatment of dementia in mammals | BEECHAM GROUP P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| US-5110828-A | Treatment or prophylaxis of dementia | BEECHAM GROUP P.L.C. (GB) | 1992-05-05 | — | — | US | disclosed |
| EP-0402056-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |
| EP-0366304-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-05-02 | — | — | EP | disclosed |
| EP-0338723-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-10-25 | — | — | EP | disclosed |