Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049033 | 0.91 | CHRM2 (0.42) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL9458387 | 0.86 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL5242716 | 0.84 | PKM (0.39) | PKM | |
| Hydrochloric Acid SCHEMBL14742183 | 0.82 | PKM (0.37) | PKM | |
| SCHEMBL2556850 | 0.77 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790912 | 0.76 | CHRM2 (0.34) | CHRM2CHRM4CHRM1CHRM3PKM | |
| SCHEMBL14351404 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9045639 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL4198612 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7981263 | 0.75 | CHRM2 (0.40) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | claimed |
| US-5132316-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | claimed |
| EP-0287356-B1 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1996-01-24 | — | — | EP | disclosed |
| US-5217975-A | AZABICYCLIC COMPOUNDS FOR TREATING DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1993-06-08 | — | — | US | disclosed |
| US-5132316-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-07-21 | — | — | US | disclosed |
| EP-0402056-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |
| US-4971975-A | TREATMENT OF DEMENTIA; AZABICYCLOOCTANE COMPOUNDS | BEECHAM GROUP PLC (GB) | 1990-11-20 | — | — | US | disclosed |
| EP-0287356-A2 | Bridgehead substituted azabicyclic derivatives | BEECHAM GROUP PLC (GB) | 1988-10-19 | — | — | EP | disclosed |