Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557075 | 0.87 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790867 | 0.79 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790912 | 0.77 | CHRM2 (0.34) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790010 | 0.77 | CHRM2 (0.41) | CHRM2CHRM4CHRM1CHRM3USP2 | |
| SCHEMBL8790499 | 0.77 | CHRM2 (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7981263 | 0.76 | CHRM2 (0.40) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9845828 | 0.75 | CHRM2 (0.32) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3951763 | 0.74 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9458387 | 0.73 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9051821 | 0.73 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | claimed |
| US-5157160-A | Treatment of diseases of the nervous system | BEECHAM GROUP P.L.C. (GB) | 1992-10-20 | — | — | US | claimed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |
| EP-0783304-A4 | METHOD FOR TREATING ANXIETY | LILLY CO ELI (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0783304-A1 | METHOD FOR TREATING ANXIETY | ELI LILLY AND COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| US-5574053-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574029-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574028-A | SEDATIVES | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996013261-A1 | METHOD FOR TREATING ANXIETY | ELI LILLY AND COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |
| US-5157160-A | Treatment of diseases of the nervous system | BEECHAM GROUP P.L.C. (GB) | 1992-10-20 | — | — | US | disclosed |
| US-5043343-A | Certain 5-substituted-1-aza-bicyclo[3.3.3]heptanes and their pharmaceutical compositions and methods | BEECHAM GROUP P.L.C. (GB) | 1991-08-27 | — | — | US | disclosed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |