Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27109662 | 0.79 | TOP2A (0.47) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL30656996 | 0.79 | KDM4E (0.41) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL10200876 | 0.79 | KDM4E (0.41) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL17051668 | 0.76 | MAOA (0.45) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL10072720 | 0.74 | TOP2A (0.55) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL10200877 | 0.73 | KDM4E (0.42) | KDM4EHTTNCOA3ACHEHIPK2 | |
| SCHEMBL3701838 | 0.72 | CYP1A2 (0.52) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL2501659 | 0.72 | TOP2A (0.45) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL21297740 | 0.71 | KDM4E (0.47) | TOP2AMAOAKDM4EHTTPOLB | |
| SCHEMBL8404561 | 0.71 | CYP2A6 (0.52) | TOP2AMAOAKDM4EHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994365-A | BACTERICIDES; FUNGICIDES; ANTITUMOR AGENT | DIAZANS LIMITED (CA) | 1999-11-30 | — | — | US | claimed |
| WO-2001017997-A1 | SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY | DIAZANS LIMITED (CA) | 2001-03-15 | — | — | WO | disclosed |
| US-5994365-A | BACTERICIDES; FUNGICIDES; ANTITUMOR AGENT | DIAZANS LIMITED (CA) | 1999-11-30 | — | — | US | disclosed |