Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 5/20 | 0.37 |
| ▸ | CCND1 | P24385 | 5/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293876 | 0.78 | CDK4 (0.42) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL27761849 | 0.76 | NPC1 (0.56) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL9306901 | 0.75 | MAP4K4 (0.41) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL7146757 | 0.75 | NPC1 (0.55) | NPC1RAB9AGAAKMT2AALDH1A1 | |
| SCHEMBL9306192 | 0.75 | MAP4K4 (0.41) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL6883476 | 0.75 | ADORA3 (0.53) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| Water SCHEMBL28237887 | 0.75 | NPC1 (0.55) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL11707809 | 0.75 | FGFR1 (0.49) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL7981295 | 0.74 | CNR2 (0.48) | ALDH1A1 | |
| SCHEMBL30872095 | 0.73 | NPC1 (0.49) | MAP4K4CSF1RFGFR1PDGFRALTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326408-B1 | FORMING MAGNA | FINANCIERE LEA S.A.R.L. (FR) | 2001-12-04 | — | — | US | disclosed |