Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260282 | 0.86 | ALDH1A1 (0.40) | KDM4ENPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL17731650 | 0.81 | KDM4E (0.46) | AURKBKDM4EPKMNPC1RAB9A | |
| SCHEMBL27761849 | 0.80 | NPC1 (0.56) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL11707809 | 0.79 | FGFR1 (0.49) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL7146757 | 0.79 | NPC1 (0.55) | KDM4ENPC1RAB9AGAAALDH1A1 | |
| SCHEMBL9306192 | 0.79 | MAP4K4 (0.41) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL28293876 | 0.79 | CDK4 (0.42) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL6883476 | 0.79 | ADORA3 (0.53) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| Water SCHEMBL28237887 | 0.79 | NPC1 (0.55) | MAP4K4CSF1RFGFR1PDGFRALTK | |
| SCHEMBL230980 | 0.77 | NPC1 (0.49) | MAP4K4CSF1RFGFR1PDGFRALTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |