SCHEMBL7981352

SCHEMBL7981352

Cn1c(=O)c(Cc2ccc(C#N)cc2)nc2c(NS(=O)(=O)c3ccccc3)cccc21

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 3/20 0.47
RXFP1 Q9HBX9 1/20 0.46
BRPF1 P55201 11/20 0.44
BRD1 O95696 7/20 0.44
BRPF3 Q9ULD4 7/20 0.44
BRD9 Q9H8M2 4/20 0.43
BRD4 O60885 3/20 0.43
BRD7 Q9NPI1 1/20 0.43
SLC40A1 Q9NP59 2/20 0.41
SLC22A12 Q96S37 1/20 0.41
MAPT P10636 2/20 0.41
TRIM24 O15164 1/20 0.41
AGTR1 P30556 1/20 0.40
PAX8 Q06710 1/20 0.40
HSD11B1 P28845 1/20 0.40
SMARCA2 P51531 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8026661 0.87 GLO1 (0.49) GLO1RXFP1BRPF1BRD1BRPF3
SCHEMBL8109694 0.83 GLO1 (0.48) GLO1RXFP1BRPF1BRD1BRPF3
SCHEMBL8026558 0.81 GLO1 (0.48) GLO1BRPF1BRD4SLC40A1SLC22A12
SCHEMBL7981348 0.80 BRPF1 (0.56) BRPF1BRD1BRPF3BRD9BRD4
SCHEMBL8017545 0.80 F2 (0.48) GLO1BRPF1BRD4SLC40A1SLC22A12
SCHEMBL8032287 0.78 GLO1 (0.44) GLO1BRD4SLC40A1SLC22A12AGTR1
SCHEMBL8028576 0.78 CDC25A (0.48) GLO1SLC40A1SLC22A12MAPTAGTR1
SCHEMBL8029909 0.78 F2 (0.49) GLO1RXFP1BRPF1BRD1BRPF3
SCHEMBL8026444 0.77 GLO1 (0.46) GLO1BRD4SLC40A1SLC22A12AGTR1
SCHEMBL8032159 0.74 MAPT (0.48) GLO1BRD4SLC40A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6200976-B1 FOR TREATING THROMBOSIS BOEHRINGER INGELHEIM PHARMA KG (DE) 2001-03-13 US disclosed