Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | VHL | P40337 | 1/20 | 0.32 |
| ▸ | ELOC | Q15369 | 1/20 | 0.32 |
| ▸ | ELOB | Q15370 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14265252 | 0.86 | GFER (0.36) | GFERALDH1A1GAACRBNKDM4E | |
| SCHEMBL29778228 | 0.84 | PDE3B (0.38) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL14090164 | 0.82 | HTR2A (0.33) | ALDH1A1KDM4EHTR2BVHLELOC | |
| SCHEMBL7984892 | 0.80 | HTR2B (0.46) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL7979696 | 0.80 | HTR2B (0.46) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL31436222 | 0.79 | VHL (0.35) | VHLELOCELOB | |
| SCHEMBL23837196 | 0.79 | EGFR (0.35) | HTR2BVHLELOCELOB | |
| SCHEMBL31145720 | 0.78 | PDE4B (0.39) | CRBNHTR2BIKZF3TDP1MEN1 | |
| SCHEMBL20169652 | 0.78 | PDE4B (0.39) | CRBNHTR2BIKZF3TDP1MEN1 | |
| SCHEMBL31151941 | 0.78 | PDE4B (0.39) | CRBNHTR2BIKZF3TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |