Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 8/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984892 | 1.00 | HTR2B (0.46) | HTR2BHTR2CHTR2AALDH1A1HSD17B10 | |
| SCHEMBL7981364 | 0.80 | GFER (0.36) | HTR2BALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL31151995 | 0.79 | ALPL (0.33) | HTR2BHTR2CHTR2A | |
| SCHEMBL31151912 | 0.79 | ALPL (0.33) | HTR2BHTR2CHTR2A | |
| SCHEMBL31151953 | 0.78 | PDE4B (0.42) | ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL31152007 | 0.78 | PDE4B (0.42) | ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL26772677 | 0.76 | HTR2B (0.52) | HTR2BHTR2CHTR2AALDH1A1HSD17B10 | |
| SCHEMBL7979737 | 0.73 | HTR2B (0.49) | HTR2BHTR2CHTR2AALDH1A1HSD17B10 | |
| SCHEMBL7980119 | 0.73 | HTR2B (0.49) | HTR2BHTR2CHTR2AALDH1A1HSD17B10 | |
| SCHEMBL18473617 | 0.72 | HTR2B (0.49) | HTR2BHTR2CHTR2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |