Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | S100B | P04271 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826402 | 0.85 | HPGD (0.50) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8390975 | 0.82 | ADRB1 (0.66) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22818552 | 0.82 | ADRB1 (0.66) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2874530 | 0.81 | ADRB1 (0.71) | LMNAALDH1A1HTTADRB1KDM4E | |
| SCHEMBL30206103 | 0.81 | MAPT (0.58) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL806757 | 0.81 | MAPT (0.58) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6223137 | 0.81 | GAA (0.65) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8864170 | 0.81 | GAA (0.65) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6273294 | 0.81 | GAA (0.65) | HPGDMEN1KMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2874114 | 0.80 | ADRB1 (0.69) | MAPTHTTADRB1TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |