Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983570 | 0.85 | LCK (0.65) | LCK | |
| SCHEMBL7987206 | 0.74 | LCK (0.65) | LCK | |
| SCHEMBL31325831 | 0.71 | GABRP (0.40) | LCK | |
| SCHEMBL31136583 | 0.71 | LCK (0.45) | LCK | |
| SCHEMBL31137728 | 0.69 | LCK (0.58) | LCK | |
| SCHEMBL31680606 | 0.69 | PKM (0.68) | LCKPKM | |
| SCHEMBL31040881 | 0.68 | FGFR1 (0.42) | LCK | |
| SCHEMBL773174 | 0.68 | HDAC1 (0.55) | LCKPKM | |
| Hydrochloric Acid SCHEMBL31137004 | 0.67 | FGFR1 (0.41) | LCK | |
| SCHEMBL30899540 | 0.67 | LCK (0.44) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |