Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751425 | 0.86 | MEN1 (0.41) | SLC6A3SLC6A2SLC6A4DHFRMPO | |
| SCHEMBL7965472 | 0.83 | MPO (0.46) | SLC6A3SLC6A2SLC6A4MPOTDP1 | |
| SCHEMBL7708396 | 0.82 | MPO (0.45) | SLC6A3SLC6A2SLC6A4MPO | |
| SCHEMBL17345636 | 0.81 | MPO (0.48) | SLC6A3SLC6A2SLC6A4MPO | |
| SCHEMBL29456377 | 0.80 | MPO (0.47) | SLC6A3SLC6A2SLC6A4MPO | |
| SCHEMBL21516391 | 0.80 | MPO (0.47) | SLC6A3SLC6A2SLC6A4MPO | |
| Hydrochloric Acid SCHEMBL21491396 | 0.79 | MPO (0.46) | SLC6A3SLC6A2SLC6A4MPOTDP1 | |
| SCHEMBL30749274 | 0.78 | MPO (0.46) | MPO | |
| SCHEMBL11465324 | 0.78 | MPO (0.46) | MPO | |
| SCHEMBL17080017 | 0.78 | KDM4E (0.46) | SLC6A3SLC6A2SLC6A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082307-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 2-SUBSTITUTED PIPERIDINE STEREOISOMERS | CELGENE CORPORATION (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999061425-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 2-SUBSTITUTED PIPERIDINE STEREOISOMERS | CELGENE CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |