Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965472 | 0.87 | MPO (0.46) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL7981639 | 0.82 | SLC6A3 (0.43) | MPOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11465324 | 0.81 | MPO (0.46) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL27347203 | 0.81 | MPO (0.46) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL17345636 | 0.81 | MPO (0.48) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL30749274 | 0.81 | MPO (0.46) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL9442019 | 0.81 | MPO (0.46) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL2554363 | 0.81 | NOS3 (0.44) | MPOMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL21516391 | 0.80 | MPO (0.47) | MPOMEN1CYP2D6CYP2C19KMT2A | |
| SCHEMBL29456377 | 0.80 | MPO (0.47) | MPOMEN1CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359139-B1 | REACTING 1-THREO-PIPERIDYL ACETAMIDE WITH AN ALKANOIC ACID IN SOLVNET | CELGENE CORPORATION | 2002-03-19 | — | — | US | disclosed |
| EP-0983238-A4 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORP (US) | 2001-08-08 | — | — | EP | disclosed |
| EP-1082307-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 2-SUBSTITUTED PIPERIDINE STEREOISOMERS | CELGENE CORPORATION (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-0983238-A1 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORPORATION (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1999061425-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING 2-SUBSTITUTED PIPERIDINE STEREOISOMERS | CELGENE CORPORATION (US) | 1999-12-02 | — | — | WO | disclosed |
| WO-1998052921-A1 | PROCESSES AND INTERMEDIATES FOR RESOLVING PIPERIDYL ACETAMIDE STEREOISOMERS | CELGENE CORPORATION (US) | 1998-11-26 | — | — | WO | disclosed |